To be able to explain the basic pathophysiology behind Pericarditis
Click to CompleteTo be able to understand the changes seen on ECG with pericarditis and apply
these to example ECGs
To demonstrate the ability to differentiate between Pericarditis and STEMI/Benign Early
Repolarisation
To demonstrate the skills learned from the above objectives via the Pericarditis Quiz
Click to CompleteThis is acute inflammation of the pericardium, the membranous sac which surrounds the heart
In most cases the pericardium becomes acutely inflamed, with pericardial vascularisation and infiltration with polymorphonuclear leukocytes
A fibrinous reaction frequently results in exudate and adhesions within the pericardial sac, and a serous or haemorrhagic effusion may develop
In some conditions (eg, tuberculosis, sarcoidosis, fungal infections and rheumatoid arthritis), a granulomatous pericarditis develops
- Widespread concave ST elevation and PR depression
throughout most of the limb leads (I, II, III, aVL, aVF) and
precordial leads (V2-6)
- Reciprocal ST depression and PR elevation
in lead aVR (± V1)
- Tachycardia is also common due to pain
• Stage 1 – widespread ST Elevation and PR depression with reciprocal changes in aVR (occurs during the first two weeks)
• Stage 2 – normalization of ST changes;
generalized T wave flattening (1 to 3 weeks)
• Stage 3– Flattened T waves become inverted (3 to several weeks)
• Stage 4 – ECG returns to normal (several weeks onwards)
It signifies to a downsloping TP segment in patients with acute pericarditis and is present in about 80% of the patients affected with acute pericarditis
The sign is often best visualized in lead II and lateral precordial leads
ST segment height = 1 mm
T wave height = 6 mm
ST / T wave ratio = 0.16
A ST / T wave ratio < 0.25 is
consistent with BER
Pericarditis can cause localised ST elevation but there
should be no reciprocal ST depression (except in AVR and V1)
STEMI, like pericarditis, can also cause concave ST elevation
Only STEMI causes convex or horizontal ST elevation
ST elevation greater in III than II strongly suggests a STEMI
PR segment depression is only reliably seen in viral pericarditis, not by other causes
It is often only an early transient phenomenon (lasting only hours)
MI can also cause PR segment depression due
to atrial infarction (or PR segment elevation in aVR)
You can’t rely on history either — STEMI
can also cause positional or pleuritic pain.
Is there ST depression in a lead other than AVR or V1? This is a STEMI
Is there convex up or horizontal ST elevation? This is a STEMI
Is there ST elevation greater in III than II? This is a STEMI
Now look for PR depression in multiple
leads… this suggests pericarditis (especially if there is a friction rub!)
ST segment height = 2 mm
T wave height = 4 mm
ST / T wave ratio = 0.5
A ST / T wave ratio > 0.25 is
consistent with pericarditis
Click to test your knowledge!